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Boron Neutron Capture Therapy (BNCT) is a type of experimental radiotherapy against cancer, with the uniqueness of being selective at the cellular level. It is based on the irradiation of the patient with neutrons, who has previously been administered a boron compound. Boron binds preferentially to cancer cells, so that when a neutron interacts with it, a nuclear reaction occurs that destroys or severely damages the cancer cell, leaving adjacent tissue cells with little damage.
In order to put this therapy into practice, it is necessary to have a neutron beam with specific qualities. To date, the energy sources used (nuclear reactors, low-energy, high-intensity accelerators) and the production reactions tested have resulted in higher energies than is required in a BNCT treatment. Therefore, a device is necessary that adapts the neutrons produced to the therapeutic needs.
Researchers from a Spanish University have developed and patented a device through which a proton beam is inserted, which interacts with a target to generate a neutron beam, a moderator that allows the neutrons to be brought up to energies in the epithermal range and a filtering stage that allows the fast neutrons, thermal neutrons and gamma radiation to be reduced.
After comparing the values obtained with those recommended by the International Atomic Energy Organization (IAEA) and with two of the main BNCT facilities (the FiR-1 reactor in Helsinki, currently dismantled, and the C-BENS in Kyoto) it is demonstrated that, thanks to the filtering stage, the device presented improves the previous designs and would be an effective solution to the problems and needs currently in the market.
The university is looking for a company related to medical, BNCT or irradiation technology specialised in oncology treatment in order to reach a license agreement for the patented technology.
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